Endocrine Abstracts

Introduction: Increased mean platelet volume (MPV) is an independent risk factor for thromboembolism, stroke and myocardial infarction. In this study we tried to emphasize the importance of gender difference in evaluation of relationship between MPV and serum biochemical parameters in type 2 diabetic patients.Methods: A total of 509 patients with diabetes mellitus who hospitalized due to several causes were retrospectively evaluated. Age, gender, other c...

Introduction: In this study we aimed to examine the risk factors associated with mortality of pneumonia among diabetic seniors in Turkish general population.Material and methods: After excluding individuals from other minorities, elderly diabetic patients who had been hospitalized due to pneumonia in recent three years consisted of study population. A total of 610 subjects aged 65 years or older were retrospectively analyzed and 196 patients who had no m...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant genetic disorder characterized by parathyroid adenomas, enteropancreatic endocrine tumors and anterior pituitary adenomas. It is caused by inactivating mutations of the MEN1 tumor suppressor gene, encoding menin (chromosome 11q13). A large family with several members affected were evaluated for clinical and genetic characteristic of MEN1.The index male patient (42 yr) presented ...

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age. Clinical and biochemical characteristics are similar to metabolic syndrome. Insulin resistance in patients with metabolic syndrome, is associated with serum uric acid levels. In our study, we aimed to investigate the relationship between serum uric acid levels and clinical and laboratory in PCOS patients.Materials and Method: PCOS ...

Aim: Euthyroid sick syndrome can be described as abnormal findings on thyroid function tests that occur in the setting of a nonthyroidal illness (NTI) without preexisting hypothalamic-pituitary and thyroid gland dysfunction. In this study we tried to compare thyroid function tests between patients with acute kidney injury (AKI) and healthy controls.Materials and Methods: This study consisted of 31 patients with AKI and 26 healthy controls. All patients&#...

Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron and sodium and water homeostasis. Patients with hypothryoidism can have clinically important reductions in glomerular filtration rate (GFR). 41 patients (mean age 31.5±11 years) newly diagnosed as Hashimoto thyroiditis with presence of high thyroid autoantibodies with gland heterogenity in ultrasound and a...

Introduction: Dyskeratosis congenita is a rare multisystemic disease characterised with atrophy on skin, pigmentation, nail dystrophy, leukoplakia in mucous membrane, bone marrow failure, and tendency to malignancy. We present a rare case of dyskeratosis congenita associated with hypothyroidism and hypogonadism.Case: A 30-year-old male patient was referred to Endocrinology Department with the findings of micropenis and atrophic testicles. His parents had...

Objective: Thyroid incidentaloma is a common endocrinological disorder. Current literature regarding the risk of thyroid cancer in incidentalomas found in patients with non-thyroid cancer is limited. The aim of the present study was to investigate the frequency of thyroid malignancy in thyroid incidentalomas detected in patients with non-thyroid cancer.Methods: The database of 287 thyroid nodules from 161 patients with a history of non-thyroid cancer fol...

Thrombocytopenia can be seen rarely in Graves disease (GD). In this report we present a case of pseudothrombocytopenia in a 21-year-old woman who had hyperthyroidism due to GD. A 21-year-old female admitted to our clinic with symptoms such as hair loss, anxiety, nervousness and tremor in hands. Considering her symptoms, thyroid function tests were evaluated to screen for presence of hyperthyoidism. Her TSH level was low while free T3 and free T4 levels we...

Introduction: Ectopic ACTH secretion by pheochromocytoma causing Cushing’s syndrome has been reported rarely. Here, we present a patient with ectopic ACTH-dependent Cushing’s syndrome, caused by a pheochromocytoma with normal fractionated 24 h urinary catecholamines and metanephrines.Case report: A 48-year old female patient admitted to our clinics with the complaints of severe hypertension despite receiving anti hypertensive therapy. Severe he...